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Contents · Categories · Featured content · A–Z index Linezolid is a synthetic antibiotic used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics. A member of the oxazolidinone class of drugs, linezolid is active against most Gram-positive bacteria that cause disease, including streptococci, vancomycin-resistant enterococci, and methicillin-resistant Staphylococcus aureus. The main indications of linezolid are infections of the skin and soft tissues and pneumonia (particularly hospital-acquired pneumonia), although off-label use for a variety of other infections is becoming popular. Discovered in the late 1980s and first approved for use in 2000, linezolid was the first commercially available oxazolidinone antibiotic. As of 2009, it is the only marketed oxazolidinone, although others are in development. As a protein synthesis inhibitor, it stops the growth of bacteria by disrupting their production of proteins. Resistance to linezolid has remained very low since it was first detected in 1999, although it may be increasing. When administered for short periods, linezolid is a relatively safe drug; it can be used in patients of all ages and in people with liver disease or poor kidney function. (more...) Recently featured: Her Majesty's Theatre – Battle of Edson's Ridge – Diocletianic Persecution From Wikipedia's newest articles: September 14 More anniversaries: September 13 – September 14 – September 15 A false-color far-infrared composite image of the Andromeda Galaxy, the nearest spiral galaxy to the Milky Way. The image consists of 11,000 separate exposures taken by the Spitzer Space Telescope's Multiband Imaging Photometer at 24 microns. The image is dominated by emission from hot cosmic dust; this is the sharpest image ever taken of this component of the interstellar medium in another galaxy. This is in dramatic contrast to the more-familiar view at visible wavelengths, which is dominated by starlight. Recently featured: Singel canal – Jacqueline Kennedy Onassis – Memorials and services for the September 11 attacks Wikipedia is hosted by the Wikimedia Foundation, a non-profit organization that also hosts a range of other projects: This Wikipedia is written in English. Started in 2001, it currently contains 3,033,775 articles. Many other Wikipedias are available; some of the largest are listed below. aswath.com

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